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MED64 Probes Request QuoteDownload Brochure
       

MED Probes

MED Probes

The standard MED probe has 64 planar microelectrodes arranged in an 8 x 8 grid embedded in the center of a transparent glass plate. Four models with inter-electrode spacings of 100, 150, 300, and 450 µm enable measurements of fine detail from small regions to larger scale interactions across regions. Each electrode is 50 µm x 50 µm in size for 150, 300, and 450 µm spacing configuration and 20µm x 20 µm for 100 µm spacing configuration, which yields a very low impedance (typically 7k ohms to 10k ohms respectively) critical to achieve a good signal to noise ratio.


Impedance of Pt. black electrode on the MED probe (red)
compared with the completely flat electrode (blue)

Special arrangements are available with Hexagonal pattern (Electrode size: 20µm, inter-electrode spacing: 70 µm) and Hippocampal pattern (CA1, CA3, & DG, Electrode size 50 µm diameter, inter-electrode spacing: 150 µm).

Hexagonal array was originally developed in the Pine lab at Caltech (Regehr et al., J. Neurosci. Meth. 1989, 30: 91-106). Hippocampal conformal array was originally developed in the Berger lab and the Tanguay lab at USC (Berger et al., IEEE EMBS Special Issue: Toward Biomimetic Microelectronics as Neural Prostheses, 2005, 24, 30-44., Gholmieh et al., J. Neurosci. Meth. 2006, 152 116-129). The present Hippocampal pattern array was designed by the Kawato lab at the University of Tokyo (Mukai et al., J. Neurochemistry. in press).

MED Probe Multi-electrode Dish MED-P515A (zoom view)
MED Probe Multi-electrode Dish MED-P515A (zoom view)
MED-P2H07A (zoom view) MED-P5001A (zoom view)
MED-P2H07A (zoom view) MED-P5001A (zoom view)
MED-P5001A (zoom view) MED-P5D15B

Standard 8x8 array

Available in two chamber depth and four inter-electrode spacings

Part Number Array size Electrode size Interpolar Distance Reference Chamber Depth
MED-P2105 0.7x0.7mm 20 µm 100 µm 8.5 mm 5 mm
MED-P210A 0.7x0.7mm 20 µm 100 µm 8.5 mm 10 mm
MED-P5155 1 x 1 mm 50 µm 150 µm 8.5 mm 5 mm
MED-P515A 1 x 1 mm 50 µm 150 µm 8.5 mm 10 mm
MED-P5305 2 x 2 mm 50 µm 300 µm 9.2 mm 5 mm
MED-P530A 2 x 2 mm 50 µm 300 µ m 9.2 mm 10 mm
MED-P5455 3 x 3 mm 50 µm 450 µm 10.2 mm 5 mm
MED-P545A 3 x 3 mm 50 µm 450 µm 10.2 mm 10 mm

Special arrangement

Hexagonal arrangement (61 electrodes)

Part Number Electrode size Interpolar Distance
Reference
Chamber Depth
MED-P2H075 20 µm 70 µm 8.5 mm 5 mm
MED-P2H07A 20 µm 70 µm 8.5 mm 10 mm

Hippocampal Pattern Arrays (CA1, CA3, & DG)

Part Number

Electrode size Interpolar Distance Reference Chamber Depth
MED-P50015 For Rat 50 µ m 150 µ m 8.5 mm 5 mm
MED-P5001A For Rat 50 µ m 150 µ m 8.5 mm 10 mm
MED-P50025 For Mouse 50 µ m 150 µ m 8.5 mm 5 mm
MED-P5002A For Mouse 50 µ m 150 µ m 8.5 mm 10 mm

2- 4x8 Array Probe NEW!

The 64 electrodes are patterned in two blocks (32 electrodes, each). It allows you to record from separate areas in a slice. Minimum order quantity: 10 pcs.

Part Number Pattern Electrode size Interpolar Distance (smallest) Distance between electrodes block Chamber Depth
MED-P50035 2-(4x8) 50 µm 150 µm 12 mm 5 mm
MED-P5003A 2-(4x8) 50 µm 150 µm 12 mm 10 mm

Dual-Chamber Probe NEW!

The 64 electrodes are patterened in two separate chambers divided by partition placed in the center of the ring. (32 eleectrodes are patterened in each chamber.) It allows you to record from 2 cultures simultaneously using one MED probe and will speed up your experiment.The probe is availabe in two types of partition-height. (5mm, 10mm). Minimum order quantity: 10 pcs.

Part Number Pattern Electrode size Interpolar Distance (smallest) Distance between electrodes block Chamber Depth Partition Height
MED-P5D15A 2-(4x8) 50 µm 150 µm 12 mm 10 mm 10 mm
MED-P5D15B 2-(4x8) 50 µm 150 µm 12 mm 10 mm 5 mm

Specifications

Substrate
Glass Substrate:
50 x 50 x 0.7 mm
Glass cylindrical chamber:
ID=22, OD=25 mm
Conducting layer:
Indium tin oxide (ITO) (0.15 µm)
Insulation layer:
Polyacrylamide (1.4 µm)

Recording/stimulating electrode
Number of electrodes:
64 (61 for MED-2H###)
Material:
ITO + Platinum Black
Size:
50 x 50 µm
20 x 20 µm (MED-P210#)
Diameter: 20 mm (MED-P2H07#)
50 mm (MED-P5001# & P5002#)
Impedance:
<22 k ohm (Typical: 7 k ohm) (MED-P5####)
<30 k ohm (Typical: 10 k ohm) (MED-P2####)
(1kHz, 50 mV applied sinusoidal wave)
Maximum voltage: 1 V
Maximum current:
200 µA, 0.1 msec

Reference electrodes
Number of electrodes: 4
Material: ITO + Platinum Black
Size:
200 x 200 µm
Diameter 100 µm x 4 (MED-P2H07#, MED-P5001#)
Impedance:
<2.2 k ohm (1kHz, 50mV sinusoidal wave)

(1) Standard 8x8 array

Available in two chamber depth and four inter-electrode spacings
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