 |
MED Probes
The
standard MED
probe has 64 planar microelectrodes arranged in
an 8 x 8 grid embedded in the center of a transparent
glass plate. Four models with inter-electrode spacings
of 100, 150, 300, and 450 µm enable measurements
of fine detail from small regions to larger scale interactions
across regions. Each electrode is 50 µm x 50 µm
in size for 150, 300, and 450 µm spacing configuration
and 20µm x 20 µm for 100 µm
spacing configuration,
which yields
a very low impedance
(typically 7k
ohms to 10k
ohms respectively)
critical to achieve
a good signal
to noise ratio.
Impedance of Pt. black electrode on the MED probe (red)
compared with the completely flat electrode (blue)
Special arrangements
are available
with Hexagonal
pattern (Electrode
size: 20µm, inter-electrode spacing: 70 µm)
and Hippocampal
pattern (CA1, CA3, & DG, Electrode size
50 µm diameter,
inter-electrode
spacing: 150 µm).
Hexagonal array was originally developed in the Pine lab
at Caltech (Regehr et al., J. Neurosci. Meth. 1989, 30: 91-106).
Hippocampal conformal array was originally developed in the
Berger lab and the Tanguay lab at USC (Berger et al., IEEE
EMBS Special Issue: Toward Biomimetic Microelectronics as
Neural Prostheses, 2005, 24, 30-44., Gholmieh et al., J.
Neurosci. Meth. 2006, 152 116-129). The present Hippocampal
pattern array was designed by the Kawato lab at the University
of Tokyo (Mukai et al., J. Neurochemistry. in press).
| MED
Probe Multi-electrode Dish |
MED-P515A
(zoom view) |
 |
 |
| MED-P2H07A
(zoom view) |
MED-P5001A
(zoom view) |
 |
 |
| MED-P5001A
(zoom view) |
MED-P5D15B |
 |
 |
Standard
8x8 array
Available in two chamber depth and four inter-electrode spacings
| Part
Number |
Array
size |
Electrode
size |
Interpolar
Distance |
Reference |
Chamber
Depth |
| MED-P2105 |
0.7x0.7mm |
20 µm |
100 µm |
8.5
mm |
5
mm |
| MED-P210A |
0.7x0.7mm |
20 µm |
100 µm |
8.5
mm |
10
mm |
| MED-P5155 |
1
x 1 mm |
50 µm |
150 µm |
8.5
mm |
5
mm |
| MED-P515A |
1
x 1 mm |
50 µm |
150 µm |
8.5
mm |
10
mm |
| MED-P5305 |
2
x 2 mm |
50 µm |
300 µm |
9.2
mm |
5
mm |
| MED-P530A |
2
x 2 mm |
50 µm |
300 µ m |
9.2
mm |
10
mm |
| MED-P5455 |
3
x 3 mm |
50 µm |
450 µm |
10.2
mm |
5
mm |
| MED-P545A |
3
x 3 mm |
50 µm |
450 µm |
10.2
mm |
10
mm |
|
|
Special arrangement
Hexagonal arrangement (61 electrodes)
| Part Number |
Electrode
size |
Interpolar
Distance |
Reference |
Chamber Depth |
| MED-P2H075 |
20 µm |
70 µm |
8.5
mm |
5 mm |
| MED-P2H07A |
20 µm |
70 µm |
8.5
mm |
10 mm |
|
Hippocampal Pattern Arrays (CA1,
CA3, & DG)
| Part
Number |
|
Electrode
size |
Interpolar
Distance |
Reference |
Chamber
Depth |
| MED-P50015 |
For
Rat |
50 µ m |
150 µ m |
8.5
mm |
5 mm |
| MED-P5001A |
For
Rat |
50 µ m |
150 µ m |
8.5
mm |
10 mm |
| MED-P50025 |
For
Mouse |
50 µ m |
150 µ m |
8.5
mm |
5 mm |
| MED-P5002A |
For
Mouse |
50 µ m |
150 µ m |
8.5
mm |
10 mm |
|
2- 4x8 Array Probe NEW!
The 64 electrodes are patterned in
two blocks (32 electrodes, each). It allows you to record
from separate areas in a slice. Minimum order quantity: 10
pcs.
| Part
Number |
Pattern |
Electrode
size |
Interpolar
Distance (smallest) |
Distance
between electrodes block |
Chamber Depth |
| MED-P50035 |
2-(4x8) |
50 µm |
150 µm |
12
mm |
5
mm |
| MED-P5003A |
2-(4x8) |
50 µm |
150 µm |
12
mm |
10
mm |
|
Dual-Chamber Probe NEW!
The 64 electrodes are patterened in
two separate chambers divided by partition placed in the
center of the ring. (32 eleectrodes are patterened in each
chamber.) It allows you to record from 2 cultures simultaneously
using one MED probe and will speed up your experiment.The
probe is availabe in two types of partition-height. (5mm,
10mm). Minimum order quantity:
10 pcs.
| Part Number |
Pattern |
Electrode
size |
Interpolar
Distance (smallest) |
Distance
between electrodes block |
Chamber Depth |
Partition Height |
| MED-P5D15A |
2-(4x8) |
50 µm |
150 µm |
12 mm |
10 mm |
10 mm |
| MED-P5D15B |
2-(4x8) |
50 µm |
150 µm |
12 mm |
10 mm |
5 mm |
|
|
|
Specifications
Glass Substrate:
50 x 50 x 0.7 mm
Glass cylindrical chamber:
ID=22, OD=25 mm
Conducting layer:
Indium tin oxide (ITO) (0.15 µm)
Insulation layer:
Polyacrylamide (1.4 µm)
Number of electrodes:
64 (61 for MED-2H###)
Material:
ITO + Platinum Black
Size:
50 x 50 µm
20 x 20 µm
(MED-P210#)
Diameter:
20 mm (MED-P2H07#)
50 mm (MED-P5001# & P5002#)
Impedance:
<22 k ohm (Typical: 7 k ohm) (MED-P5####)
<30
k ohm (Typical: 10 k ohm) (MED-P2####)
(1kHz, 50 mV applied
sinusoidal wave)
Maximum voltage:
1 V
Maximum current:
200 µA,
0.1 msec
Number of electrodes: 4
Material:
ITO + Platinum Black
Size:
200 x 200 µm
Diameter 100 µm
x 4 (MED-P2H07#, MED-P5001#)
Impedance:
<2.2 k ohm (1kHz,
50mV sinusoidal wave)
(1) Standard 8x8 array
Available in two
chamber depth and four inter-electrode spacings |
|
