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MED64 System
Acquire continuous, reliable,
long-term evoked and spontaneous activity across 64 channels
with two-dimensional, real-time analysis of neuronal/ myocardial
activity.
Features
Simultaneous recording across 64 channels
• Signals
(evoked potentials and/or spontaneous activity) are acquired
across an array of 64 micro-electrodes patterned on the
patented MED probe.
• Any
electrodes on the array (up to four) and/or external
electrodes can be used for stimulation.
• MED64 system can be
used in conjunction with patch clamping, microscopic
visualization of cells, or other methods used to examine functional activity
(e.g. Ca++ imaging).
Easy to use and ready to go
• User friendly software
guides you through experimental setup, including stimulation
parameters and/or drug testing, as well as data recording
and analysis.
• Stimulus sites can be switched quickly and easily
on the front panel of the MED64 amplifier. • The
MED64 system does not require a special shielded environment..
Long-term observation
• Dissociated cells
and slice explants can be cultured directly on the MED
probe.
• The MED probe and connector can be placed in a humidified
incubator.
• Responses can be recorded for days to months without
any damage by planar electrodes.
Components
MED
64CH Integrated
Amplifier
• Reliable,
low-noise, 64 channel
amplifier based
on Panasonic "Technics" high
fidelity audio
technology
• High-bandwidth
of 0.1Hz-10kHz
allows users to
record several
types of extracellular
potentials
• Samples
at a max rate of
20 kHz/ch Built-in
stimulator allows
users to study
the effects of
realistic spatio-temporal
stimulation patterns
by programming
complex induction
sequences from
any of the four
built-in stimulation
units and two external
inputs
• Fast, easy
switching of simulation
sites
MED64 Connector
• Used for communication
between the MED64
probe and amplifier
• Provides a stable
platform for the
MED64 probe
• Multi-layer
electrical shielding
rejects hum noise
and provides excellent
signal-to-noise
ratios
• No onboard
electrical circuits;
connectors can
be placed in high-humidity
environments
MED Probes
• Biological acute
or culture preparations
are placed directly
into the MED probe
• The MED probe allows
users to stimulate
and record from
samples using planar
microelectrodes
Several types of
arrays are available:
• 8x8 (64) electrode
arrays are available
with four different
inter-electrode
spacing’s;
100, 150, 300 and
450 µm. Each
patented microelectrode
measures 50 µm
x 50 µm -
except for the
100 µm spacing
configuration,
with microelectrodes
measuring 20 um
x 20um.
• 61 electrode
hexagonal arrays
are available with
70 µm inter-electrode
spacing. The electrodes
are circular (20 µm
diameter).
• Two
special arrays,
designed specially
for simultaneously
stimulating/recording
from the dentate
gyrus (DG), CA3
and CA1 are available
for mouse (8 weeks
old) and rat (16
weeks old).
• Probes
come in 5 mm (for
use with synchronized
glass electrode
recording) and
10 mm well heights
• Probes use Panasonic's
Liquid Crystal
Display technology
MED64 Performer™ and
MED64 Conductor ™ Software
• MED64 Performer™ Software's easy-to-follow
wizards make conventional electrophysiology accessible to researchers
from a wide range of disciplines. These wizards contain parameter
settings for data collection and analyses that are used in
several commonly used experimental paradigms.
• MED64 Conductor™ Software
is designed for the advanced user who is familiar with electrophysiology.
It enables users to exploit the full potential of the MED64
system in part by allowing users to program sophisticated
stimulation sequences. Other features include a real-time,
64-channel oscilloscope (at sampling rate of 20kHz/channel),
with continuous 64- channel recording for up to -30 days
(limited only by disk storage size). Conductor provides many
off-line measurement functions (e.g. average, peak amplitude
and slope calculations).
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