 |
MED64 System
Acquire continuous, reliable,
long-term evoked and spontaneous activity across 64 channels
with two-dimensional, real-time analysis of neuronal/ myocardial
activity.
Features
Simultaneous recording across 64 channels
• Signals (evoked
potentials and/or spontaneous activity) are acquired across
an array of 64 micro-electrodes patterned on the patented
MED probe.
• Any electrodes on the array (up to four) and/or
external electrodes can be used for stimulation.
High
S/N recording and various applications
• Because of the
low-impedance of micro-electrodes (typically 7-10 k ohm at
1 kHz), signals can be acquired easily even from acute slices.
• It is well
suited for experiments on acute slice as well as slice (and
dissociated) cultures. It is the powerful solution for drug
evaluation.
• It is possible to acquire slow-wave signals such
as fEPSP or even signals from smooth muscle tissue (around
0.1 Hz) as well as high-frequency signals such as spike activities.
Low Noise and Easy-to-use
• Because of its
low-impedance-electrodes, the MED64 system does not require
special shielded environment. It creates high data reproducibility.
• Stimulus sites can
be switched quickly and easily on the front panel of the
MED64 amplifier.
• User friendly and highly sophisticated software
guides you through experimental setup including stimulation
parameters as well as data recording and on-line (off-line)
analysis.
Long-term observation
• Dissociated cells
and slice explants can be cultured directly on the MED probe.
• MED probe and connector can be placed in humidified
incubator. Because of the low-impedance of electrodes, the
MED64 system needs no blocking pre-amplifier required on
connector.
• Responses can be recorded for days to months
without any damage by planar electrodes.
Components
MED
64CH Integrated
Amplifier
• Reliable,
low-noise, 64 channel
amplifier based
on Panasonic "Technics" high
fidelity audio
technology
• High-bandwidth
of 0.1Hz-10kHz
allows users to
record several
types of extracellular
potentials
• Samples
at a max rate of
20 kHz/ch Built-in
stimulator allows
users to study
the effects of
realistic spatio-temporal
stimulation patterns
by programming
complex induction
sequences from
any of the four
built-in stimulation
units and two external
inputs
• Fast, easy
switching of simulation
sites
MED64 Connector
• Used for communication
between the MED64
probe and amplifier
• Provides a stable
platform for the
MED64 probe
• Multi-layer
electrical shielding
rejects hum noise
and provides excellent
signal-to-noise
ratios
• No onboard
electrical circuits;
connectors can
be placed in high-humidity
environments
MED Probes
• Biological acute
or culture preparations
are placed directly
into the MED probe
• The MED probe allows
users to stimulate
and record from
samples using planar
microelectrodes
Several types of
arrays are available:
• 8x8 (64) electrode
arrays are available
with four different
inter-electrode
spacing’s;
100, 150, 300 and
450 µm. Each
patented microelectrode
measures 50 µm
x 50 µm -
except for the
100 µm spacing
configuration,
with microelectrodes
measuring 20 um
x 20um.
• 61 electrode
hexagonal arrays
are available with
70 µm inter-electrode
spacing. The electrodes
are circular (20 µm
diameter).
• Two
special arrays,
designed specially
for simultaneously
stimulating/recording
from the dentate
gyrus (DG), CA3
and CA1 are available
for mouse (8 weeks
old) and rat (16
weeks old).
• Probes
come in 5 mm (for
use with synchronized
glass electrode
recording) and
10 mm well heights
• Probes use Panasonic's
Liquid Crystal
Display technology
MED64 Mobius™
• MED64 Mobius™ software is the data acquisition
and analysis software for the MED64 system with an abundant
set of analysis functions. It is a highly-sophisticated software
and suits several types of experimental needs.
• MED64 Mobius™ is available in various package
including "EP measurement" and "Spike Sorter" as
well as a combined package. It is flexible software consisting
of various "modules". Users can design their own
experimental workflow by using "Mobius editor", while
they start with simple experiment quickly by using various "Mobius
templates".
Mobius QT
New Mobius QT package allows MED64 users to acquire and analyze myocardial signals online and offline. It is the perfect solution for QT screening with iPS/ES cell derived myocytes.
MED64 System Set
|
|
|
|
