PolyAn Functionalized Glass Slides

PolyAn is proud to offer one of the broadest product portfolios of microarray substrates on the market. Our products include plastic and glass slides as well as functionalized 96-well plates for DNA-, peptide- or protein microarrays. Applications range from low density microarrays for diagnostic tests to ultra-high density arrays for pharma screening.

The slides are produced with standard dimensions of 25 x 75 x 1 mm. Additionally, we offer customized slides and alternative glass formats with surface modifications tailored to your specific application.

For cost-sensitive applications PolyAn has developed a range of 2D (2-dimensional)-reactive glass slides that are manufactured from high quality glass with an ultra-flat surface and low inherent fluorescence. The glass is coated with a thin silane layer that will covalently bind most types of bio-molecules. The defect-free surface features uniform silane layers that provide a high covalent coupling efficiency together with a very low background. The slides are easy to use, and are fully compatible with all commercially available arraying and scanning instruments.

PolyAn’s 3D-functionalised microarray Slides are functionalized with a three-dimensional (3D)-surface chemistry comprised of a long-chain polymer containing a defined number of reactive groups. This polymer is covalently linked to the surface of the slide.

Our MSE-technology gently binds the functional layer onto the surface without damaging the base substrate. The morphology of the functional surface and thus the number of the reactive groups can be fine-tuned within a narrow range. This yields a number of advantages:

Low fluorescence background
Covalent binding of functional layer on the substrate without changing the initial autofluorescence.

Low unspecific binding
Combination of reactive functional groups with PolyAn antifouling matrix.

Topography
Tuneable surface
hydrophilicity / hydrophobicity (contact angle).

Uniform spot morphology
Narrow variation of surface properties and homogeneous distribution of reactive groups.

Optimal density and high accessibility of reactive groups
Morphology and thickness of functional layer tailored to the desired application.